Enko Bacteriophage Annotation
Description
ENKO bacteriophage is a mixture of sterile filtrates of phagocytes of the following bacteria:
- Shigella flexneri (1, 2, 3, 4, 6 serovans) and Sh. sonnei
- Salmonella (typhimurium, enteritidis, heidelberg, newport, cholera suis, oranienburg, Dublin, anatum)
- Enteropathogenic Escherichia coli
- Staphylococcus aureus
- ENKO bacteriophage is a transparent white or yellowish liquid
Pharmacologic effect
Causes specific lysis of following bacteria species:
Shigella flexneri, shigella sonnei, Salmonella typhimurium, Salmonella enteritidis, Salmonella choleraesuis, Salmonella oranienburg, Salmonella Newport, Salmonella Dublin, Salmonella anatum; enteropathogenic Escherichia coli, Staphylococcus aureus.
Prescription
ENKO bacteriophage is used for treatment and prophylaxis of purulent-septic and enteric infections caused by the above-mentioned microorganisms.
Indictions
Gastrointestinal infectious diseases: gastroenterocolitis, dysbacteriosis (bacterial overgrowth syndrome); cholecystitis, staphylococcal toxic infection; dysentery.
Recommended doses of ENKO bacteriophage are as follows:
| Age | Per os/Per Day | Per rectum/Per Day |
| Infants 0-6 months | 5ml 1 time, 30 min before feeding | 10ml once a day |
| Kids 6-12 months | 5ml 2 times, 30 min before feeding | 10ml once a day |
| Kids 1-3 years | 5ml 3 times, 1 hour before the meal | 20ml once a day |
| Children 3-8 years | 10ml 2-3 times, 1 hour before the meal | 30ml once a day |
| Children older than 8 years, adults | 20 ml 2-3 time, 1 hour before the meal | 40ml once a day |
Treatment should continue for 6-10 days.
Before taking ENKO bacteriophage, it is recommended to take a glass of basic mineral water (or 2-3% solution of baking soda).
Contra-Indications: There are no contraindications ever observed for ENKO bacteriophage. The use of ENKO bacteriophage does not exclude concomitant use of antibiotics or any other medicine.
Special Precautions: Before use, the ampoule must be shaken. The liquid must be clear, without sediment.
If the ampoule is damaged, or if the liquid is cloudy, the preparation should not be used.
The preparation should be used immediately after the ampoule or flask has been opened, Once opened it should not be saved for later use.
Packaging and Store Conditions: The preparation is presented in 5 ml ampoules.
Storage temperature +2 - + 8 C
Expiration - 1 year
Developed by: G. Eliava Institute of bacteriophage, Microbiology and virology.