ENTEROFURYL

Pharmacological properties
Nifuroxazide is a derivative of 5-nitrofuran, which is not absorbed from the gastrointestinal tract and has antimicrobial and antiparasitic action throughout the intestinal tract. Nifuroxazide is thought to trap bacteria and then kill intestinal infectious bacteria through the sodium-NO2 group. Gram-positive Streptococcus pyogenes and Staphylococcus pyogenes are particularly susceptible to nifuroxazide as well as gram-negative enterobacteria E. coli, Salmonellae and Shigellae, which cause diarrhea.

Pharmacokinetics
After oral administration, nifuroxazide is practically not absorbed from the gastrointestinal tract and its antimicrobial effects are manifested in the intestinal tract. Nifuroxazide does not penetrate into the organic system and tissues. It is fully excreted in the feces. The rate of expulsion depends on the amount of drug taken and the ability of the digestive tract to move. However, it can generally be said that the excretion is slow and nifuroxazide stays in the digestive tract for quite a long time.

Indications
- diarrhea caused by alimentary infections and intoxications in children and adults, in particular, caused by E. coli;
- Chronic diarrhea during colitis;
- Disruption of intestinal fermentation;
- Acute and chronic diarrhea of ​​nonspecific and unknown etiology without invasive events;
- Iatrogenic diarrhea caused by taking antibiotics;
- Some cases of coagulopathy with specific bacteria.
- Symptomatic diarrhea with colorectal cancer;
- Prevention of traveler's diarrhea.

Storage conditions and terms: Keep out of reach of children.

Shelf life: 3 years. The drug should not be used after the expiration date.

Conditions of release: Out of prescription.